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Drug Name
Plavix (clopidogrel)
Drug Uses
Clopidogrel is used to prevent the Strokes and heart attacks in people who are at high risk. In one large study, clopidogrel was more effective than aspirin in reducing heart attack. The frequency of side effects of clopidogrel to aspirin was similar, however, stomach and intestinal bleeding probably less frequent with clopidogrel and aspirin.
How to use
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Take clopidogrel exactly as directed physician. Clopidogrel may be taken with or without food. If you do not understand these instructions, ask your pharmacist, nurse or doctor to explain them. Take each dose with a full glass of water.
Drug Class and mechanism
Clopidogrel’s anti – platelet drug, that is, a drug that inhibits the ability to suppress Platelets together as part of a blood clot. This is similar tiklopidine (tiklid) in chemical structure and the way it works. Unlike tiklopidine, paxil can cause severe price reductions of white blood cells in the blood, and therefore, routine blood testing to determine whether white blood cell count is low, it is not necessary during treatment. The risk of heart attack and Stokes (usually they are caused by blood Klotz) was increased in patients with a recent history of stroke or heart attack and patients with peripheral vascular disease. (Peripheral Vascular disease is the same as atherosklerotik arterial disease or “Hardening” of the arteries which become Narrowed arteries. Appears often in the legs and often causes pain in klaudikatyon or hopped walking). Clopidogrel is used to reduce the risk of heart attack and Stokes in the patients. Clopidogrel has been approved by the FDA in 1997.
Missed Dose
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Take the missed dose as soon as you remember. Do not take a double dose of this medicine. However, if it is almost time for the next dose, skip the missed dose and take only the regularly scheduled dose.
Storage
Tablets should be stored at room temperature, 15-30 ° C (59-86 degrees F), away from moisture and heat.
Warnings / Precautions
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Tell your doctor and dentist to take your medicine before Living in surgical procedures. Do not take aspirin, ibuprofen (motrin, Advil, nuprin, others), naproxen (Aleve, anaprox, naprosyn, others), ketoprofen (out, out hi, orvuail) indomethasin (indosin), nabumetone (relafen), oxaprozin (daypro) , or other non – steroidal anti – inflammatory drugs (NSAIDs) start Talk with your doctor. This may take a long time, as usual for you to keep bleeding even from minor wounds. Tell your doctor about any unusual bleeding or bruising that experience. Studies in rats have shown that clopidogrel appears in breast milk, however, is not known whether it also appears in breast milk. Because of the potential for adverse effects in the baby, the doctor needs of potential benefits and possible risks before prescribing clopidogrel in nursing mothers.
Possible side effects
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Tolerabiliti is clopidogrel was similar to that of aspirin. Diarrhea, rash, or itching appears in about 1 in 20 people clopidogrel. Abdominal pain also occurs in about 1 in 20 people, but is less common than aspirin.
Tiklopidine (tiklid) is antiplatelet Pharmaceuticals quite similar to clopidogrel. This was associated with severe reduction in white blood cell count in between 0.8% and 1% of the people. The risk of dangerous side effects with clopidogrel is about 0.04%, much less than with tiklopidine, but twice that of aspirin.
Causes clopidogrel rare condition called thrombotik thrombositopenik purple (kind of) in one out of every 250,000 people. Type is a serious condition in which blood clots form throughout the body. Blood platelets, which are consumed to participate in a Keating, and the result can be bleeding because there is not enough Platelets have long left to allow normal blood Klatt. For comparison, related drugs, tiklodipine (tiklid), causes a pot 17-50 times more frequently than clopidogrel.
More information
If you experience any of the following serious side effects, take clopidogrel and seek emergency medical attention or notify your doctor immediately:
Allergic reaction (difficulty breathing: Closing of the throat, swelling of the lips, tongue or face or hives);
Bloody (or black) vomit or Chairs;
Severe headache, confusion, or dizziness;
Unexplained bruising or bleeding, or
Bleeding nose.
Other, less serious side effects May be more likely to occur. Continue to take clopidogrel and talk to your doctor if you have
Upset stomach;
Diarrhea or constipation, or
Headache or dizziness.
Side Effects other than those listed here also appear in May. Talk to your doctor about any side effect that seems unusual or that is especially boring.
